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Abstract of the Article

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evaluation of exposed to benzene and compare level of trans,trans-muconic acid in taxi drivers and petrol station workers

Authors:
[ Hasan Ahmadi ] -
[ AbdolRahman Bahrami ] -
[ Ahmad Joneydi Jafari ] -
[ Hossein Mahjoub ] -

Abstract:

The environmental concentrations of benzene have increased significantly in the last years due to increased, road traffic. The major sources of benzene in ambient air of urban area are car exhaust and evaporation loss during handling, distribution and storage of petrol.The major environmental problem in Iran is air pollution, there are about of 6 million vehicles in Iran and 40% of them are at least two decades old. The petrol pump stations in Iran are besides of street and workers in this location did the pumping and services of fuel. During their daily work, workers have direct contact with petroleum products, so occupational exposure to benzene cannot be avoided. The aims of this study were evaluation of exposed to benzene and compare level of trans,trans-muconic acid in taxi drivers and petrol station workers with a control group in West of Iran. Methods: A detailed questionnaire was completed for study and control participants, providing information about personal characteristics, smoking and food habits.The benzene in air was analyzed with a gas chromatography equipped with a Flame Ionization Detector. Trans,Trans-Muconic acid was extracted from urine and analyzed with high performance liquid chromatography. Results:The significant differences in the levels of urinary T,T-MA were found in drivers and petrol station workers compared to the control group (p<0.0001). The correlation coefficients between benzene in air and T,T-MA for petrol station workers and drivers were r = 0.77 respectively. The concentration of benzene in breathing zone of petrol station workers was 3-4 times higher than drivers and also 3 times greater than the threshold level (0.5 ppm) recommended by the American Conference of Governmental Industrial Hygienists (ACGIH). Conclusion:In conclusion our results was showed high hydrocarbons levels emitted in petrol stations and means of transport in Iran. T,T-MA could separate the exposed to benzene from the non-exposed when benzene in breathing zone of subjects was less than 1ppm.We suggest that extensive attention to benzene exposure is needed for maintaining the health of gasoline station workers.

Keywords:

Trans Trans –muconic Acid ,Bio Marker,Metabolit