Evaluation of Apoptosis-related pathways and their relevance to cancer

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CBGCONF03_027

تاریخ نمایه سازی: 8 آبان 1395

چکیده مقاله:

Apoptosis is a genetically controlled form of cell death that is essential for tissue remodeling during embryogenesis and for maintenance of the homeostatic balance of cell numbers later in adult life. The importance of apoptosis to human disease comes from the realization that disruption of the apoptotic process is thought to play a role in diverse human diseases ranging from malignancy to neurodegenerative disorders. Because apoptosis is a genetically controlled process, much effort has been spent on identifying these genetic components to better understand the apoptotic process as well as to identify potential therapeutic targets that might be manipulated in disease conditions where disruption of apoptosis occurs But the role of the cytoplasmic organelles during apoptosis signaling pathways and their interactions in typical studies done and published papers are not complete or comprehensive.Aim: The purpose of this paper is to examine some molecular mechanisms involved in the process of apoptosis and other pathways related to it.

نویسندگان

Milad Vahedi

Young Researchers and Elite Clube, Borujerd Branch, Islamic Azad University, Borujerd, Iran

Atieh Babaei

Young Researchers and Elite Clube, Borujerd Branch, Islamic Azad University, Borujerd, Iran

Soodeh Mir Mohammadi

Department of Biology, Faculty of sciences, Kurdistan University , Kurdistan, Iran

Maria Farahnak

Department of Physiology, Faculty of sciences, Kurdistan University , Kurdistan, Iran

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