Title: synthesis of nanogels contained graphene oxide based on (N-Iso propyl acrylamide), and their applications in drug delivery

Synthesis of Nano gels which contain graphene oxide based on N-isopropyl acryl amide is done in order to controlled release Doxorubisin drug. Also, morphology, size of Nano gels and drug releasing are surveyed. In this project, N-isopropylacrylamide monomer is a temperature sensitive compound and acts as a smart material. Results show that releasing drug by this synthesized Nano gel is controllable and also this releasing drug from Nano gel network is compatible with pH environment. The goal of this project is to, 1. synthesis of nanogels contains Graphene oxide via a new method, 2. use N-isopropyl acrylamide monomer for making smart system, 3.identify nanogels by the usage of different technics like SEM, TEM, 4.survey of nanogels’ applications indrug releasing. The reason of using 3 pH for drug releasing is the compatibility of these pH withintestine acidity.

کلیدواژه ها:

drug releasing ، Doxorubisin ، Nano gel ، Graphene oxide ، N-isopropyl acrylamide ، Salep