Synthesis of functionalized dialkyl 6-(alkylhexylamino)-3-formyl- 1,2,3,4-tetrahydro-2-oxopyrimidine-4,5-dicarboxylate through the reaction of isocynides with actived acetylenes in the presence of nformyluea

The reaction between alkyl(cycloalkyl) isocyanides and dialkylacetylene dicarboxylate in the presence of nformylurea leads to dialkyl 6-(alkylhexylamino)-3-formyl- 1,2,3,4-tetrahydro-2-oxopyrimidine-4,5-dicarboxylate in high yields.

کلیدواژه ها:

isocyanide ، dialkylacetylenedicarboxylate ، nformylurea ، oxopyrimidine