Reaction between 2-amino benzophenone and dialkyl acetylenedicarboxylate in the presence of silica gel in solvent-free condition

A two-component condensation reaction between an 2-amino benzophenone and an electron-poor acetylenic ester efficiently provides fully substituted electron-poor quinoline-2,3-dicarboxylic acid dialkyl ester in a one-pot reaction in the presence of silica-gel in solvent-free conditions.

کلیدواژه ها:

Acetylenic ester ، Quinoline ، Solvent-free ، Silica-gel