Application of nanofiltration membranes in the separation of Amoxicillin from pharmaceutical wastewater

Separation of amoxicillin from pharmaceutical wastewater by nanofiltration membranes was studied. For this purpose a membrane system including a polyamide nanofiltration (NF) membrane was evaluated for the treatment of amoxicillin wastewater. The effect of the operating conditions such as flow rate, pressure and concentration of the feed on the efficiency of the membrane was evaluated. The permeation flux and rejection of amoxicillin were the criteria for this evaluation. The rejection of the amoxicillin by the selected NF membrane is adequate and in most cases exceeds 97% whereas COD reached a maximum of 40% rejection. Permeation flux was over 1.5 lit/min.m2. The rise in pressure enhanced the transport rate of the solvents. Permeate flux of membrane increased with increasing flow rates. Experimental data indicated that concentration polarization existed in this membrane separation process. The results are consistent with the NF mechanism of pressure-driven physical processes DQGVROXWLRQ±GLIIXVLRQFKemical processes. The stable separation performance for long-time operation showed that this kind of membrane has a good solvent resistance and could have a potential application in concentrating pharmaceutical extracts

کلیدواژه ها:

Amoxicillin ، Membrane ، Nanofiltration ، Rejection ، Retentate