Improvement of operating conditions for preparation of gelatin electrospun fibers used in tissue engineering

In the current research, electrospun gelatine fibers was successfully fabricated. The gelatin solutions were prepared with different amount of gelatin (10, 15, 20 and 25% wt) which dissolved in different ratios of co-solvent acetic acid / water (1:9, 1:3 and 1:1). Also various voltages applied for desired solutions to obtain the optimum voltage. The experiments showed the best conditions for electrospinning of the gelatin solution in where the concentration was 25% wt gelatin while it was dissolved in the ratio of 1:9 (v/v) water/ acetic acid and the applied voltage was 23 or 25 kV. The SEM images revealed the average size of diameter were about 190 and 210 nm, respectively

کلیدواژه ها:

gelatin ، electrospinning ، solvent ، fibrous scaffold ، tissue engineering