Effect of water and sediment mercury pollution of Persian Gulf on some health indices of Yellowfin Seabream

Two important physiological processes which are modulated when fish are exposed to chemical for regaining safe homeostasis, are hormonal status and immune function, but there is few knowledge about role of serum hormones and biochemical parameters during mercury exposure of fishes, so in this study, a multi factorial approach, involving determining thyroid and testosterone hormones along with serum total protein and glucose during the in vitro exposure of mercury chloride was used. According to the LC50 test, fish divided in 5 treatments. All serum hormones were assayed using diagnostic ELISA direct immuno enzymatic kits. Serum glucose and total protein was measured photometrically. Values recorded for activity of total protein show high significance depletion (P<0.01) with mercury exposed. Although glucose was increase in different treatment, but there was not find significant variation. Both T3 and T4 activities exhibited significant analysis of variance (P<0. 05) with lower considerable values than those of the control group for T3 and higher considerable values than those of the control group for T4. No significant changes occurred in the activities of the Testosterone, however it was decreased. Results of the present investigation indicated that mercury is a toxic substance in yellowfin seabream, with cause several changes in the serum biochemical and hormonal parameters of fish exposed to various concentrations