The effect of vitamin D on male and female fertility disorders

Background: We know the role of vitamin D in protecting calcium and phosphorus homeostasis and bone mineralization. Vitamin D can improve reproduction ability and modulator process of reproductive system in women and men. In healthy women, the rate of vitamin D is higher than women with polycystic ovary syndrome (PCOS) because the vitamin D receptor is placed in the endometrium , myometrium, ovarian and cervix.Methods: In this review article, we tried to express the role of vitamin D in reproduction processes and its function in infertility therapy. We searched about key words vitamin D, infertility, PCOS at google scholar and pubmed.Result: The result of this review article concerned the vitamin D role in infertility treatments and its effect of treatment in women with PCOS, uterine fibroid , infertility and in men with inefficient semen. Vitamin D deficiency can cause gonadal insufficiency, decreased sperm count and motility and abnormalities of testis, ovary, uterus and it can be a reason for PCOS. In PCOS, loss of 25-(OH)D levels can be the reason for obesity, metabolic and endocrine disorders. In addition, men with vitamin D shortage had a lesser ratio of motile, progressive motile, and morphologically common spermatozoa contrasted with men with enough vitamin D situation.Conclusion: In the recent studies, appearing data offered that vitamin D is not the single critical factor for the retention of bone safety but also imposes multisystem regulative effects that adjusts throughout health and wellbeing. A growing body of writing offers that Vitamin D can impact reproductive actions.

کلیدواژه ها:

Infertility ، Ovarian insufficiency ، Reproductive ، Semen ، Vitamin D