MECHANICAL، CHEMICAL AND BIOLOGICAL FACTORS IN BONE RESORPTION PROCESS

In this paper, a new model for bone resorption using mixture theory in combination with thermodynamics with internal variables is proposed. hree constituents (matrix, fluid and cells) are considered. Conservation equations (mass, momentum and energy) are provided for each constituent and for the whole mixture. Entropy inequality for the mixture is also given. The rate of mass transfer between phases, caused by chemical eactions, is assumed to be a function of extent of chemical reactions, deformation gradient, temperature and temperature gradient. Using constitutive equations in the 2nd law of thermodynamics, a new criterion for the thermodynamics equilibrium state is concluded.

کلیدواژه ها:

Mixture theory ، Bone resorption ، Chemical affinity ، Resorbing cells