Plasmacytoid Myoepithelioma of the Palate with Rapid Growth: A Case Report

سال انتشار: 1386
نوع سند: مقاله ژورنالی
زبان: انگلیسی
مشاهده: 610

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شناسه ملی سند علمی:

JR_IJP-2-3_006

تاریخ نمایه سازی: 5 آبان 1393

چکیده مقاله:

Myoepitheliomas are benign tumors which account for less than 1% of all salivary gland tumors. In this article, we report the clinical, pathologic, and immunohistochemical features of plasmacytoidmyoepithelioma of the hard palate in a 73-year-old man having a painless hard palate mass withprogressive growth for one month who was admitted in Alzahra Hospital of Isfahan University of Medical Sciences. The patient underwent a complete surgical resection of the tumor. Lightmicroscopy showed a nodule with sharp margins of large cells with plasmacytoid aspect presentinground eccentric nuclei and an abundant and homogenous eosinophilic cytoplasm arranged in sheetsand groups separated by an abundant, loose, myxoid and hyalinized matrix. Immunohistochemistrywas performed on formalin-fixed and paraffin-embedded tissue with a panel of immunohistochemical markers comprising cytokeratin (CK), vimentin, S100, actin and EMA. Tumor cells showed strong and diffuse positivity for S100 and also CK, vimentin, and actin, but confirming the myoepithelial origin of the tumor, EMA immunostaining was negative

نویسندگان

Ardashir Talebi

Dept. of Pathology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Fatemeh Pooralborzi

Dept. of Pathology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Hamid Reza Ghasemi Basir

Dept. of Pathology, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran

Ahmad Reza Okhovvat

Dept. of Ear, Nose and Throat, Alzahra Hospital, Isfahan University of Medical Sciences, Isfahan, Iran