TOXOPLASMA GONDII INFECTION IN CANCER PATIENTS IN GUILAN

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 461

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شناسه ملی سند علمی:

MEDISM19_443

تاریخ نمایه سازی: 13 مهر 1397

چکیده مقاله:

Background and Aim:Toxoplasma infection in immunocompromised individuals, such as individuals malignant patient under chemotherapy, can cause severe disease as encephalitis or systemic infections. This report is first study about prevalence of Toxoplasmosis in cancer patients in Guilan-North of Iran.Methods:This Case control study was performed on Cancer patients referred to Educational Hospital in Rasht (North of Iran), from July 2017 to January 2018. Blood samples were collected from 148 cancer patients having different types of malignancies would like to contribute in our study, as well as 150 immunocompetent individuals as a control group, to assess the seroprevalence of anti-T.gondii antibodies.Results:The antibodies (IgG/IgM) were measured by ELISA method. Overall, 71 cases were female and 79 cases were male. The results showed that one patients (1/148) (IgG+, IgM+) with acute phase, 94/148 (%) (IgG+, IgM-) chronic phase and 1/148 (%) (IgG-, IgM+) false positive.Conclusion:These data showed high percent of patients were susceptible to reactivation of latent toxoplasmosis. For this reason, it is important that patients with toxoplasmosis infection are diagnosed and identified in order to refer them for early therapy or other interventions.

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نویسندگان

Mohammad Reza Mahmoudianloo

Cellular and Molecular Research Center, Guilan University of Medical Sciences, Rasht- Iran

Ebrahim Rajabi

Faculty of medicine, Guilan University of Medical Sciences, Rasht- Iran

Farshid Saadat

Faculty of medicine, Guilan University of Medical Sciences, Rasht- Iran