A glance to Mesenchymal stem cells, and Mesenchymal stem cells, which can derive from adipose tissue

Stem cells are non-specialized and undifferentiated biological cells in living bodies which sometimes named as mother cells, have high potential of division, and can be differentiated under special physiological circumstances or in the presence of special factors to yield a variety of matured cells or specialized tissues. These cells can divide into two groups of adult stem cells and embryonic stem cells. Mesenchymal stem cells are adult stem cells and will participate in repairing tissue, such as bone, cartilage, muscle, tendons and adipose tissues. MSCs possesses the property of heterogenetic and fibroblastic, and are self-renewal and can be differentiated. Mesenchymal stem cells has three main features in invitro: Plastic adherence, the ability to differentiate into adipose, osteoblaste and cartilage, the expression of surface markers CD73, D90, CD105 and lack of expression of the markers CD14, CD34, CD45. Over the years, many initial and most flourished studies were performed on MSc, which were separated from bone marrow; in recent years Mesenchymal stem cells are obtained of various tissues such as umbilical cord blood, Wharton's jelly, amniotic fluid and adipose tissue, but the use of adipose tissues have become common due to few special characteristics such as easy access, great texture and high Proliferation. Adipose tissue derived Mesenchymal stem cells have the power to differentiate into a variety of tissues. These cells can also be used in tissue engineering and cell therapy. Thus, this study aims to express few specific characteristics of MSCs isolated from adipose tissues

کلیدواژه ها:

Stem cell ، Mesenchymal stem cells ، Adipose tissue