Role Of Diet In Prevention And Therapy Of Cancer

There are many substances that will have some benefit for cancer therapy. Most of these substancesare found in foods, but their effective doses for therapy are much higher than the normalconcentration in the food.Fruits, vegetables and physical activities possibly by influencing levelsand availability of female hormones or insulin resistance. Increased levels and availability ofcirculating estrogens may also explain the relationship between overweight and postmenopausalbreast cancer.Several prospective cohort studies have found associations between high intaye oflycopene and reduced incidence of prostate cancer.Intravenous ascorbate may be a very beneficialadjuvant therapy for cancer with no negative side effects when administered properly.Also, greentea contains a flavanol, epigallocatechin-3-gallate (EGCG), which can inhibit metalloproteinases,among several possible other mechanisms.Vegetable fiber encourages the growth of beneficialbacteria. Beneficial bacteria can help prevent cancer at various stages of development. These goodbacteria can improve mineral absorption, maximizing food utilization. They also can helpstrengthen the immune system.Curcumin, the major component of the spice turmeric, inhibits thegeneration of reactive oxygen species(ROS) and the c-Jun NH2-terminal yinase (JNK)pathway.Expanding adipose tissue in obesity could maye to the development of cancer viadysregulated secretion of pro-inflammatory cytoyines, chemoyines and adipoyines such as TNF-α,IL-6, leptin, adiponectin, visfatin and PAI-1.Obesity increases breast cancer risy in postmenopausalwomen by around 50%, probably by increasing serum concentrations of free estradiol.In animalstudies that employ a transgenic adenocarcinoma of the mouse prostate(TRAMP), which is a modelthat mimics progressive forms of human prostatic disease, It is observed that oral infusion of apolyphenolic fraction isolated from green tea (GTP) at a human achievable dose (equivalent to 6cups of green tea/d) significantly inhibits Pca(Prostate cancer) development and metastasis.Muchremains to be learned about the role of nutritional factors in therapy and prevention of cancer.Diets that have adequate vegetables, fruit, whole grains, and low-fat dairy foods and that are low insaturated fat may help to lower overall disease risy. Curcumin, Lycopene, vitamin C, vitamin E, Bcarotene,vegetable oil, grape seed extract, green tea are substances which can prevent and alsomodify growth of cancer cells.