Effect of surfactant concentration and lipid: oil ratio on the particlesize and stability of beta carotene nano lipid carrier
محل انتشار: بیست و سومین کنگره ملی علوم و صنایع غذایی ایران
سال انتشار: 1394
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 782
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شناسه ملی سند علمی:
NCFOODI23_218
تاریخ نمایه سازی: 6 اسفند 1395
چکیده مقاله:
The objectives of the present study are to prepare and produce betacarroten -contained NLCs, andsurvey the effect of surfactant concentration and lipid: oil ratio on the particle size and stability ofbetacarotene NLC. The Hot-High shear Homogenizer (Hot-HSH) technique was applied to produceNLC dispersions and the optimum formulation determined with different circumstances change,such as surfactant concentration (2, 3, 4 and 6% w/v) and lipid:oil ratio (Compritol ATO 888/ octyloctanoate) in 2:1,4:1and 10:1. Various testes such as particle size, morphology and stability carriedout to determine physicochemical properties of formulations. NLCs prepared at 3% (w/v)poloxamer 407 concentration and at 10:1 ratio of compritol (solid lipid) to octyl octanoate (liquidoil) containing 2% (w/v) beta carotene concentration showed significantly lower particle size andnarrow particle size distribution (73 nm and span = 0.684, respectively). The results showed that anoptimum concentration of 3% of Poloxamer 407 was sufficient to cover the surface of nanoparticlesefficiently and use 10:1 ratio of solid lipid liquid oil showed significantly lower particle sizecompare to other ratios . The production of betacarroten-contained NLCs was an efficacious methodin terms of encapsulation, nanoscale particle size decrease, stability within time and other expectedspecifications
کلیدواژه ها:
نویسندگان
Maryam Banaye Zirak
Department of agriculture, Mamaghan branch, Islamic Azad University, Mamaghan, Iran
Akram Pezeshki
Asssistant Professor of department of Food Science and Technology, Faculty ofAgriculture, University of Tabriz, Tabriz, Iran
Maryam Mohammadi
PHD student of department of Food Science and Technology, Faculty ofAgriculture, University of Tabriz, Tabriz, Iran
Isa Fathollahi
Department of agriculture, Mamaghan branch, Islamic Azad University, Mamaghan, Iran