Investigation of the Relationship Between Silver Sulfadiazine and Nitrofraasone Dressing in Burn Patients in Imam Khomeini Hospital, Urmia

Background: Burn is a major contributor to child mortality in developing countries. Burns are the third leading cause of accidental deaths in all age groups and the second cause of injury in the age group of up to 6 years. Silversulfadiazine and nitrofurazone have been found on many organisms. Gram positive and negative has bactericidal effect and is used to treat infections of burn wounds. Silversulfadiazine and Nitrofurazone are used in grade 2 and 3 burns and skin lesions and skin infections. The aim of this study was to evaluate the relationship between silver sulfadiazine and nitrofraasone dressing in burn patients in Imam Khomeini Hospital of Urmia. Material and Methods: Our statistical population included 68 patients with burns referring to burn ward of Urmia Imam Khomeini Hospital. Patients were divided into three groups. The first group included patients who were dressed with silver sulfadiazine daily, the second group was those who were dressed only with nitrofurase, and the third group was those who were dressed together with silverosulfadiazine and nitrofuraseon one day, and the results were collected The data were analyzed by SPSSV.24 using Chi-square test Results: Frequency of patients in the group treated with sulfosulfadiazine was (P = 0.001 OR = 17.55% CL = 95.7), which indicates a significant relationship. In the second group, frequency (CL95 = 11.17, OR = 0.17) % 18.66), which showed a low correlation with the incidence of improvement and in the third group, no significant correlation was observed (OR = 21.19 OR = 45.22, 95% = 95.29) for the presence of infection based on There were no significant correlations between the clinical signs of microbiology between the three groups (P> 0.001). Also, there was no significant relation between epithelization and the number of days of admission with the disease (P> 0.001). Conclusion: Based on the results, dressings in patients with burns of fluids showed a high improvement compared to the drug sulfosulfadiazine, indicating that the choice of medication for the treatment of burn patients should be done with high precision.

کلیدواژه ها:

Burn ، Silversulfadiazine ، Nitrofurazone ، Infection