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گواهی نمایه سازی مقاله Pharmacological properties of some 3-substituted indole derivatives, a concise overview

عنوان مقاله: Pharmacological properties of some 3-substituted indole derivatives, a concise overview
شناسه (COI) مقاله: JR_ICC-2-4_007
منتشر شده در فصلنامه ارتباطات شیمی ایران در سال ۱۳۹۳
مشخصات نویسندگان مقاله:

Kobra Nikoofar - Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891176, Iran
Diba Kadivar - Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891176, Iran
Samaneh Shirzadnia - Department of Chemistry, School of Science, Alzahra University, Vanak, Tehran 1993891176, Iran

خلاصه مقاله:
Indole is a nitrogen-containing heterocycle. It is a very important motif in agriculture and pharmacy. Many compounds containing indole moiety have been isolated form nature. It is also animportant part in natural alkaloids. Tryptophan is an amino acid which posses indole. 3- Sustituted indoles are the main group of its derivatives. Because the wide-spread application of 3-substituted indolic compounds, their synthetic procedures are in demand by organic chemists. In this review, we have focused on about twenty compounds of 3-substituted indole derivativesthat showed pharmacological properties. A concise synthetic route for some of them has also been reported. The main pharmaceutical properties of these compounds are antibacterial, anticancerand antimicrobial activities.

کلمات کلیدی:
Indole, indolyl, pharmacy, drug, synthesis

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