Jahanshahi - Nanobiotechnology Lab., Faculty of Chemical Engineering, Mazandaran University, Babol, Iran.
Tobi - Nanobiotechnology Lab., Faculty of Chemical Engineering, Mazandaran University, Babol, Iran.
Kiani - Electochemical Lab., Departments of Chemistry, Mazandaran University, Babolsar, Iran.

This paper addresses recent advance in electrochemical pretreatment of Carbon-Nanotubes (CNT) based Nanobiosensors. CNT which has been produced by different processes, i.e. arc-discharge and chemical vapor deposition (CVD), subjected to the electrochemical activation. As for ARCCNT the anodic pretreatment resulted in a dramatic improvement in the electrochemical reactivity (cycle Voltammetric test in 1.5 V) while CVD-CNT appeared to be resistant to the anodic activation. Such a huge difference was illustrated through NADH, ascorbic acid hydrogen peroxide and hydrazine model redox systems. The influence of the pretreatment potential and time is examined. The results herein offer a better understanding of the electrochemical reactivity of CNT. Common design of CNT-based Nanobiosensors along with practical examples of such novel devices is strongly discussed.

Electrochemical Pretreatment, Carbon Nanotube, Cycle Voltammogram, Nanobiosensor