Mohammed Reza Shadmand Foumani Moghadam - Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Sharif Etemadi - Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Federico Bozzetti - Faculty of Medicine, University of Milan, Milan, Italy.
Mohammad Amushahi - Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Reyhane Bakhshipour - Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Parnian Pezeshki - Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Majid Ghayour-Mobarhan - Metabolic Syndrome Research Center, Mashhad University of Medical Sciences, Mashhad, Iran.
Majid Khadem-rezaiyan - Department of Community Medicine and Public Health, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Khashayar Khanizade - Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.
Luciana B Sutanto - Faculty of Medicine, Krida Wacana Christian University, Jakarta, Indonesia.
Gordon Ferns - Division of Medical Education, Brighton, and Sussex Medical School, Falmer, Brighton, BN۱ ۹PH, Sussex, UK.
Zohreh Hosseini - Department of Nutrition Sciences, Varastegan Institute for Medical Sciences, Mashhad, Iran.

Introduction : Sarcopenia is characterized by weakness of the skeletal muscles. This study aimed to evaluate the prevalence of sarcopenia and its relationship with dietary intake, socioeconomic status, depression, lifestyle, and physical activity for the first time in a well-nourished over ۵۵ year’s old population. Methods: This study was conducted on a well-nourished above ۵۵ years old population. The European Working Group on Sarcopenia in Older People-۲ (EWGSOP-۲) guideline was used to determine the prevalence of sarcopenia. Muscle mass was assessed using bioelectrical impedance analysis. Muscle strength and performance were evaluated using handgrip and gait speed, respectively. The dietary intake, socioeconomic status, psychological health, lifestyle, clinical factors, and physical activity were examined using valid tools. Results: A total of ۷۶۶ well-nourished individuals (mean age=۶۵.۱۴±۶.۸۴ years old; male:female ratio= ۱:۱.۹۹) were evaluated for sarcopenia. The prevalence of pre-, confirmed-, and severe sarcopenia were ۲۳.۹%, ۱.۸%, and ۱.۳%, respectively. Age was significantly related to sarcopenia (OR=۱.۰۹۶ (۹۵% CI: ۱.۰۶۹-۱.۱۲۴), p<۰.۰۰۱). Females had an increased risk of pre-sarcopenia (OR=۲.۱۸۹ [۹۵% CI: ۱.۴۸-۳.۲۳۹], p=۰.۰۰۲), while males were at higher risk of confirmed and severe sarcopenia (OR=۱۵.۱۰۲ [۹۵% CI: ۴.۴۶۱-۵۱.۱۳۱], p<۰.۰۰۱). The decision tree model of sarcopenia indicated age as the main predictor for sarcopenia. Conclusion: According to EWGSOP-۲, the overall prevalence of sarcopenia was ۲۷% among well-nourished almost healthy elderly population. There was a relationship between age and sarcopenia. Females and males were at higher risk of pre-sarcopenia and confirmed and severe sarcopenia; respectively. Further research is strongly suggested to asses pre-sarcopenia.

sarcopenia, Geriatric, Aging, Prevalence, Iran, Pre-sarcopenia