اعظم عبدالهی - School of Rehabilitation, Shahid Beheshti University of medical sciences, Tehran, Iran.
مرتضی طباطبایی فر - Department of Radiation Oncology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
مهدی طباطبایی - School of Rehabilitation, Shahid Beheshti University of medical sciences, Tehran, Iran.
محمد آقازاده امیری - School of Rehabilitation, Shahid Beheshti University of medical sciences, Tehran, Iran.
احمدرضا مافی - Department of Radiation Oncology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran

Background and Aims: The aim of this study was to compare refractive error, uncorrected and corrected distance visual acuity (UDVA and CDVA) changes in patients with different types of cancer before and after completing the course of systemic chemotherapy Material and Methods: Sixty-four right eyes of ۶۴ consecutive patients with cancer were evaluated prospectively to compare the changes of UDVA and CDVA using standard Snellen chart and refractive errors using objective refraction before and after chemotherapy process. Results: The mean age of patients was ۵۲.۷± ۱۲.۹ (range, ۲۷-۸۰) years [۲۸(۴۳.۸%) males, and ۳۶ (۵۶.۳%) females]. The most changes in refractive error were found in hyperopic patients in the component of “spherical equivalent” (۰.۶۹±۱.۳۴) and “spherical” (۰.۶۱±۲.۳۷) refractive error after the first course of chemotherapy. However, the other changes in deferent refractive error groups were under -۰.۲۵ diopter. Although the spherical refractive error in all patients’ groups decreased, these reductions were not statistically significant (P>۰.۰۵). On the other hand, in all patients’ groups, the amount of cylindrical refractive error was increased, but these changes were not statistically significant (P>۰.۰۵). Although the UDVA in different refractive error groups had insignificant changes after completing the course of chemotherapy, these changes were not statistically significant(P>۰.۰۵). In addition, the CDVA in different refractive error groups remained relatively stable following the chemotherapy process (P>۰.۰۵). Conclusion: The refractive error, UCVA and CDVA after completing the course of systemic chemotherapy remained relatively unchanged. This study revealed that in patients with cancer, the refractive error and vision are not influenced by chemotherapy medication.

Cancer, refractive error, visual acuity, chemotherapy