Afsaneh Khojastepor - Department of Medicine, Faculty of Medicine, International Campus, Shahid Sadoughi University, of Medical Sciences, Yazd.
Reyhaneh Azizi - Associate Professor, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Razieh Sadat Tabatabaei - Departmant of Obstetrics and Gynecology, Shahid Sadoughi University of Medical Sciences and Health Services, Yazd, Iran. Mother and Newborn Health Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Nasim Namiranian - Acossiat Professor of Community & Preventive Medicine, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.
Haniyeh Nikkhah - Researcher, Diabetes Research Center, Shahid Sadoughi University of Medical Sciences, Yazd, Iran.

Objective: Today, the association of blood groups as genetic traits has been confirmed in many diseases. However, its association with gestational diabetes mellitus (GDM) has not been investigated. Therefore, in this study, we investigated the relationship between blood groups and GDM. Materials and Methods: In this analytical cross-sectional study, pregnant women referred to Baqaeipur Clinic and Yazd Diabetes Research Center in ۲۰۱۵-۲۰۱۸Based on the information related to the results of the one-hour OGTT test and the two-hour glucose levels recorded in the file were divided into two groups (GDM, non GDM). Then other information about the participants in the study, including demographic information, medical history, ABO and Rh blood groups, abortion, delivery, and number of pregnancies were extracted from the file and analyzed using SPSS version ۲۳ software. Results: Out of ۱۷۰۸ pregnant women, ۲۴۴ (۱۴.۳%) had GDM, and ۱۴۶۴ (۸۵.۷%) did not. There was a statistically significant difference between these two groups in terms of age (P< ۰.۰۰۱), weight (P< ۰.۰۰۱), number of pregnancies (P< ۰.۰۰۱), delivery (P< ۰.۰۰۱), previous diseases (P< ۰.۰۰۱), and Rh (P= ۰.۰۱). While in terms of the ABO blood group system (P= ۰.۳) and abortion rate (P= ۰.۰۶۷), no statistically significant difference was observed. Conclusion: Finally, we concluded that the frequency of the B+ blood group is higher in the GDM group, however, there is no statistically significant relationship between ABO blood groups and GDM.

Blood groups, Gestational diabetes mellitus, Metabolic disease