Mohammad Hasan Sheikhha - Yazd Clinical and Research Center for Infertility, Shahid Sadughi University of Medical Sciences, Yazd, Iran.
Seyed Mehdi Kalantar - Yazd Clinical and Research Center for Infertility, Shahid Sadughi University of Medical Sciences, Yazd, Iran.
Nasrin Ghasemi - Yazd Clinical and Research Center for Infertility, Shahid Sadughi University of Medical Sciences, Yazd, Iran.

Polycystic ovary syndrome (PCOS) is a genetically based disorder which reflects multiple potential aetiologies and variable clinical presentations. It is clearly a heterogeneoussyndrome, and current proposed diagnostic criteria include a number of disorders with similar phenotypes but radically different aetiologies. The lack of well-defined diagnostic criteria makes identification of PCOS confusing to many clinicians and seriously delayed theclarification of its genetics, aetiology, clinical associations and assessment of treatment. There is no universally accepted clinical definition for PCOS. In this review the genetic causes and diagnosis criteria of PCOS will be discussed

PCOS, Heterogeneous syndrome, Genetics