Khadijeh Irandoost - Associate Professor, Department of exersice phisology, Imam Khomeini International University, Qazvin,Iran
Farzaneh Rashvand - Department of exersice phisology, Imam Khomeini International University, Qazvin, Iran
Lotfali Lotfi - Department of exersice phisology, Payame Noor University, Tehran, Iran

Obesity and related diseases are one of the most important causes of death worldwide. For better understanding of the mechanisms that cause metabolic diseases, it is necessary to pay attention to the central elements of energy balance adjustment, such as dietary intake and energy costs. Knowledge about the relationship between exercise and appetite is important both for athletes wishing to optimize performance and for those interested in maintaining a healthy body weight. Evidence suggested that chronic exercise training typically causes a partial compensation in energy intake perhaps due to changes in appetite regulating hormones.The purpose of the current review is to describe the current status of evidence about ghrelin,obestatin ,nesfatin-1 and lifestyle factors. This review is focuses on gherlin, obestatin and nesfatin-1, by first summarizing their function and their relationship with hormonal and metabolic changes that affect energy balance, and then discussing the effects of Aerobic and Resistance Physical Activity on plasma and serums gherlin, obestatin, nesfatin-1 concentrations, and the potential mechanisms involved.

Physical Activity, Appetite, Gherlin, Obestatin,, Nesfatin-1, Energy Balance, Obesity