Jalal Karimi - Epidemiology and Biostatistics Department, School of Public Health, Isfahan University of Medical Sciences

Background and Aim : The use/abuse of drugs, both legally and illegally, is a worldwide public health problem, and has serious impacts on theindividual,family,society,andcrimes. Inordertoassessthescopeof thedruguse/abuseissue,itiscritical,first,todeterminethe number of individuals using/abusing drugs, the epidemiological/demographic features of the using/abusing population, and the typeof drugsused/abused. Currently,dataontheprevalenceandincidenceof substanceabuseinIrancannotbedirectlyobtained. Weproposethenextphaseof determiningtheprevalenceandincidenceof drugabusebyintroducingsystemthinkingandsystem dynamics modeling to estimate the number of addicts, recreational drug users, and drug-related deaths. In this study, we evaluated a dynamical system approach to model drug-related deaths in the next 10 years in Isfahan province.Methods : We proposed a general model for drug abuse that can easily be specified to study the dynamics of drug-related deaths.Results : Based on the estimated parameters, we calculated the total population of Isfahan province, the future susceptible popu- lation of drug users/abusers, recreational users, and addicts, and the growth rates and death rates for the latter three groups for the years 2013 - 2023. These estimations were based on an epidemiological mathematical model to predict the proportions of drug abusers over the next ten years in Isfahan. As expected, this model shows an increase of about 10 folds in deaths related to drug abuse in addicts by 2023 and a 14% increase in the addict population in Isfahan province.Conclusion : The dynamical system approach is suitable to address the dynamic complexity of many public health issues. It has thepotentialtointegrateourawarenessaboutmultilevelcausesof healthandtheirtemplateof action,reaction,andfeedback,and to promote our knowledge about how policy interventions affect the health of communities and populations.

Dynamical System Approach, Drug Abuse, Epidemiology, Iran