English Version is Trial!

کاربران فارسی زبان لطفا به بخش فارسی مراجعه نمایند.

سیویلیکا به زبان فارسی

Advanced Search

Title
Author
(Last name)
Abstract
Keywords

About CIVILICA®

CIVILICA® provides professional papers published in national and international conferences.

This site is registered for BoomSazeh Construction Technology Development Co.

 

Contact Us:

Tel: 021-88008044

Email: Info [at]  CIVILICA [dot] com

 

 
Home Page E-mail us to: Info @ CIVILICA . com Tel: +98-21-88008044

ISSN 1735-5540   

 

Quick Search in Title, Abstract, and Keywords of Papers

Showing Abstract of PrsA Lipoprotein promotes efficient extracytoplasmic protein secretion in bacteria

 
Links

[ Bug Reporting | Back | See this Article in Persian CIVILICA ]

Paper Details

[ Abstract Viewed: | Pages: 10 ]

Title

PrsA Lipoprotein promotes efficient extracytoplasmic protein secretion in bacteria

Topic: Published Year: 1396
Presentation:
Published in:

[ 4th Congress of the development and promotion of Agricultural Sciences and Natural Resources and the Environment Iran ]

Original Language: English Full Text Size: Not Available

 

Abstract of the Article

 

Note: English CIVILICA is in its Trial Period so Full Texts can not be provided! Persian users can download it here

Download This article in PDF format PrsA Lipoprotein promotes efficient extracytoplasmic protein secretion in bacteria

 

Author:

[ Ciamak Ghazaei ] - Mohaghegh Ardabili University

 

Abstract:

This paper explores the essential function of the PrsA-mediated system of influencing the amount and rate of protein secretion from Gram positive bacteria. During secretion, bacterial proteins face an obstacle course of extremes of charge, pH, unfolding and re-folding into native conformations in order to be of service in the adaptation of the bacterial cell to its environment. Recent evidence suggests that PrsA enhances the yield and efficiency of this secretion process through its influences on protein shape and stability (as a chaperone) as well as its effects on the bacterial cell wall itself. PrsA up- or down-regulation also affects cellular levels of many other factors that exert effects on the ubiquitous Sec secretory pathway. This represents an additional avenue for manipulating Gram positive bacteria to secrete the type and amount of heterologous proteins required, whether it is large or small. The PrsA system offers an attractive target for many beneficial clinical as well as industrial applications. More work should be done to fine-tune our understanding of its mechanisms of action.

 

Keywords:

PsrA, Gram positive, protein secretion, protein folding, antibiotic resistance

 

CIVILICA® - © BoomSazeh Construction Technology Development Co.

SAVAFA