Background: There were an estimated 219 million cases of malaria in 87 countries with 435 000 deaths in 2017. The number of confirmed malaria cases reported in the Eastern Mediterranean Region decreased from 2 million in 2000 to less than one million in 2019. Iran has been classified as a malaria eliminating phase and aiming to become malaria-free by 2025. Study on malaria epidemiology is a critical component in properly targeting interventions, measuring their impact and designs of the control program Objectives: The purpose of this study has been the emphasis on epidemiology of malaria vectors in the city of Babol in Mazandaran Province northern Iran.Materials and Methods: The
Anopheles mosquitoes were collected by payrethrum space spray technique every 15 days intervals and were identified by specific systematic keys. The Epidemiological data was collected from Babolm CDC, analyzed and draw charts using Excel and SPSS software ver 20.Results: A total of 4710
Anopheles females were collected Including; An. (An) maculipennis (51%)، An. (An) pseudopictus (47 %) and An. (An) hyrcanus (2 %). Out of 86.7 % of mosquitoes caught from animal and 13.3% from human shelters. There are a significant difference and positivecorrelation between the minimum، maximum and average of daily temperature and incidence of malaria cases (P-Value <0 / 05). Non significantly was observed between the relative humidity in the morning( 08.30AM)، monthly rainfall and incidence of malaria cases (P-Value > 0 . 05) whereas، significantly difference was observed between the relative humidity around 12.30 PM. (P-Value <0 . 05) . Total of 262 malaria cases found through 1986-2009. The majority of cases were found in 1986 (18.3%) at 79.8% males and 20.2% females. Out of 58.8% were Iranian،40.8% Afghan ، 0.4% Pakistanian . Out of 77.1% living in rural areas and 22.9% were living in urban areas. 95.8% of the cases infected by P.vivax and the rest 4.2% P.falciparum . Most cases classified in age group above 15 years (88 / 5%), ABER index 4.91 % in 1986، and 0.03% in 2009. API index reached 0.12 per thousand population in 1986 to zero in the 2009 whereas، SPR index was 0.25% in 1986 has decreased to zero in 2009.Conclusion: In order to elimination the horizon of malaria until 2025 in Iran ، is recommended the implementation of similar studies in other parts of the country، particularly South and South east regions with regard to many cases of disease in these areas.