Application of Sulfamic acid@nano SiO2 as an efficient heterogeneous catalyst for synthesis of 2-amino-dihydropyranopyran-3-carbonitriles in water

An efficient one-pot green procedure for the synthesis of 2-amino-dihydropyrano[3,2-b]pyran-3- carbonitriles has been reported via three-component condensation of kojic acid, malononitrile and aldehydes in aqueous media at ambient temperature using Sulfamic acid@nano SiO2. This methodology has valuable advantages such as convenient one-pot operation, short reaction times, environmentally friendly conditions, ease of catalyst recovery and the use of water as reaction media.

کلیدواژه ها:

2-amino-dihydropyrano[3 ، 2-b]pyran-3-carbonitrile ، Multi-component reaction ، Kojic acid ، Sulfamic acid@nano SiO2