HN-01820142 _Canola, Sesame, and Sesame-Canola oils might improve body fat distribution in adults: A triple-blind, three-way randomized cross-over clinical trial

Although canola and sesame are regarded as healthy vegetable oils, limited and controversial data exist regarding their effect on body adiposity. The present study aimed to examine the effect of replacing edible oils with sesame (SO), canola (CO) and sesame-canola oils (SCO) on body weight and composition in adults. This study was designed to be a triple-blind, randomized, three-way cross-over trial. Participants without any chronic disease (n=77, ages: 47.43±1.17 year, body mass index (BMI): 28.21±0.54 kg/m2) were entered to a 4-week run-in period and then were randomized to receive SO, CO and SCO for their household use for 9 weeks. The intervention periods were separated by 4-week washout intervals. Anthropometric measurements, as well as body composition markers, were assessed at baseline, middle and after each intervention period. In total, 73 participants completed the study and 69 attended all phases. All intervention oils reduced the waist circumference (P<0.05). Also, body adiposity index and hip circumference were significantly decreased after SCO and CO periods and the consumption of SO and SCO reduced the index of central obesity (P<0.05). However, after CO consumption, body fat percent was significantly increased (P= 0.02). The same effects were seen only in females. No difference was seen in the changes in anthropometric measures between the three intervention periods. The present clinical trial revealed that sesame and canola oils might beneficially improve body fat distribution by improving central obesity without affecting body weight, particularly in females. The study protocol is registered in the Iranian registry of clinical trials (http://en.irct.ir/trial/12622) with registration code of IRCT2016091312571N6.

کلیدواژه ها:

Dietary oils ، Sesame oil ، Canola oil ، Obesity ، Body mass index ، Body weight ، Body composition