COMPARISON OF THE EFFECTS OF GREEN TEA AND MELISSA OFFICINALIS INFUSION ON WEIGHT, BLOOD PRESSURE, MARKERS OF OXIDATIVE STRESS AND INFLAMMATION IN THE WELDERS: A RANDOMIZED SINGLE-BLIND CROSSOVER CLINICAL TRIAL

Background and Aim: Increased levels of homocysteine and oxidative stress due to welding require interventions in order to solving this problem. Green tea (GT) and Melissa officinalis (MO) has been proven effective in reducing free radicals separately. This study aimed to compare the effect of them on blood pressure, oxidative stress and inflammation indicators in welders. Methods: Twenty participants of this randomized single-blind crossover clinical trial were welders of workshops of Yazd, Iran. Study period have lasted twelve weeks that 1 week run in, 4 week first phase of intervention, 3 weeks of washout and 4 weeks second phase of intervention. Blood samples were collected at the beginning and end of first and second phases. Completed demographic data, 24 hour food intake recall and international physical activity questionnaires, blood pressure and anthropometric measurements were performed at the beginning and end of each intervention.Results: However gallic acid concentration was higher in GT and higher concentrations of antioxidants was observed in MO but MO or GT infusion consumption had no significant change in anthropometry, blood pressure, inflammation and oxidative stress markers (P > 0.05).Conclusion: A possibly significant difference among the antioxidant and anti-inflammatory effects of GT and MO does not exist but further studies with larger sample sizes are appreciated.

کلیدواژه ها:

Green tea ، Melissa officinalis ، oxidative stress ، inflammation ، welders ، crossover