Performance of bone marrow transplantation center in Imam Reza hospital ,Kermanshah ,Iran

One of the best and modern achievements of medical science is transplantation an organ that in a relatively short time in the world medical history has accepted as a new and inimitable way for currying many diseases. The hematopoietic stem cell transplantation (HSCT) is needed cell intravenous infusion for reestablishing bone marrow function in diseases that bone marrow destroyed or weakened. this approach is doing as a redeemer way after chemotherapy with high dosage for malign diseases. bone marrow transplantation is the main and final therapy for many of hematologic and malign diseases such as aplastic anemia kinds of thalassemia and leukemia and hereditary metabolic disorders.During last 4 years in BMT ward at Imam Reza hospital of Kermanshah 127 successful case of bone marrow transplantation done. 66.37 % of patient done autoloug transplantation and 3863% done alogen transplantation. From this cases 29.84% of patient are women and 70.16% are men 33.87% are uneducated and others are respectively 28.84% under diploma 18.55% diploma ,7.26% of patient were alliterated,8.87 % were under the diploma and the rest of patient had college degrees. The average age of patient was 41-50 year old. MNC taken from patients in 26.42% of patients 3-5,in 50% of patients 6-8,19.81% of patients 9-11 and in the 3.77% of patients was more than11 .the blood group in the 37.1% of patients was AIn the 19.35% was B, in the 9.68% of patients was AB and 33.87% of patients was O . 91.13% of the patients was RH+ and the other was RH-. Chimerism hematopoietic in the 100% of patients was 90%.From all of transplanted patient 45.16 % affected by multiple myeloma, 16.13% Hodgkin s lymphoma 8.06% nonhodgkins lymphoma ,20.97% AML, 4.84% ALL and 2.42 % myelofibrosis ,Aplastic anemia 2.42%, Fanconi anemia 1%.90 % of patients before transplantation have not recurred. In 97.25% of patient’s, cell separation done just once. In 2.75 % of patient cell separation done twice.Obtained MNC average of patients was 6-8 %.69.81% of patient s engraftment is done between 6 to 10 days. The average received platelet of patients was 21 to 30 bags.After transplantation 90.63 % of patients did not have complication. After dismission 9.37% of patients hospitalize again due to several causes. In pursuance of patients 95.83 % continue their life without any problem .pearson correlation between CD3-CD34 is 76% and between CD3-MNC is 238 % and maximum correlation between CD34-MNC was 330%.

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BMT transplant ، cancer