Rhino-orbital mycosis in immunocompetent adult man

Rhino-orbital mycosis is a rare but life threatening infection that generally occurs in patientswith diabetes mellitus and other immune deficiency conditions. Rhino-orbital is a medicalemergency condition. Early recognition and treatment are essential because it may lead tobrain involvement. We report a 27-year-old healthy man; presented to us with left-sidedfacial swelling and bloody nasal discharge. He had normal blood sugar and negative HIVresult. Magnetic resonance imaging of the head and sinuses showed inflammation and massin the ethmoid sinus and nose with partial septal destruction, proptosis and global invasion ofthe left eye. Endoscopic biopsy of the sinuses and orbital biopsies revealed severegranulomatous inflammation with degenerated aseptate hyphae on light microscopy. Thepatient was treated with amphotericin B and multiple wound debridements along withethmoidectomy.