Clinic-pathologic patterns of diagnostic curettage in patients with abnormal uterine bleeding referring to Pasteur Hospital: 2017-2018

Aim and Background: Abnormal uterine bleeding is one of the most common gynecological problems in not pregnant women and refers to any abnormal uterine bleeding duo to various reasons such as endometrial hyperplasia, tumor and polyp. D&C is a safe, available and relatively inexpensive method with acceptable sensitivity and specifity for evaluating the most common causes of AUB especially endometrial cancers and histological diagnosis is very essential for adequate management especially in premenopausal and postmenopausal females. The aim of study was to evaluate AUB in various age groups, histopathological evaluation of endometrium and analysis the clinicopathologic patterns. Material &method: This cross sectional Study was done in Pasteur Hospital, Bam University of medical science between October 2017 to August 2018. Endometrial tissue was collected by D&C Procedure and the samples (220 cases) were sent to pathology ward for evaluation by pathologist. Patient’s data included age, parity, and abnormal bleeding pattern, contraceptive method, presence of dysmenorrhea, D&C results and histopathological findings were collected in a check list. The data were analyzed by SPSS software. Results: The study included 220 patient with the average age of 42/9 y. Endometrial polyp was the commonest pathology (34.4%) followed by hyperplasia (24.8%) and secretory endometrium (13.3%).The highest frequency of hyperplasia was seen in patient with BMI > 30 ( 32.4%) .There was no relation between severity of dysmenorrhea and pathologic diagnosis. Most cases of hyperplasia were seen in patients with 4 children (21.3%), and also in patient not using contraception method (29.3%). Conclusion: This study show increase body mass index and not using contraception have great influence on endometrial hyperplasia, the pre-cancerous lesion of endometrial cancer. Because of low rate of patient with less than 3 children, no definite relation between parity and endometrial hyperplasia identified, so more study is recommended.

کلیدواژه ها:

AUB ، D&C ، uterine bleeding pattern