The Cost-effectiveness and Cost-utility Analysis of the Use of Enoxaparin Compared with Heparin for Venous Thromboembolism Prophylaxis in Medical Inpatients in Iran
محل انتشار: دومین کنگره اروپایی آسیایی فارماکواپیدمیولوژی
سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 388
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شناسه ملی سند علمی:
AECPMED02_012
تاریخ نمایه سازی: 28 بهمن 1398
چکیده مقاله:
Purpose: The present study aims to evaluate the cost-effectiveness and cost-utility of using Enoxaparin compared to Heparin in Venous Thromboembolism (VTE) prophylaxis in medical inpatients, from payer’s perspective in Iran. Methods: To evaluate cost-effectiveness and cost-utility of the compared interventions, decision tree modeling technique was used. The main considered outcomes were Quality-Adjusted Life Years (QALY) for Cost-Utility Analysis (CUA) and Life Years Gained (LYG) for Cost-Effectiveness Analysis (CEA). Costs and consequences were evaluated for a three-month period and reported as Incremental Cost-Effectiveness Ratios (ICERs). One-way and Probabilistic Sensitivity Analysis (PSA) were conducted to evaluate the robustness of the model due to uncertainty in the input data. Results: Baseline ICERs were 60,376 USD/QALY and 71,077 USD/LYG per patient (with public tariff). The results of the sensitivity analysis showed the robustness of the model. Conclusion: As the estimated ICER per QALY is more than three times the reported Gross Domestic Product (GDP) per capita by world bank for Iran in 2017 ($5415), the use of Enoxaparin for VTE prophylaxis in medical inpatients doesn t seem to be a cost-effective intervention compared to the use of Heparin in Iran
کلیدواژه ها:
نویسندگان
mohammadreza amirsadri
Isfahan university of medical science
sarah mousavi
Isfahan university of medical science
ali karimipur
Isfahan university of medical science
mahnaz momenzadeh
Isfahan university of medical science