Efficacy of dialysis on Spirometry and IOS (5Hz and 20Hz) in patients with renal failure

Introduction: Both chronic and acute renal failure could cause the respiratory dysfunction.Since controversies exist among the few studies investigating the pulmonary function in ESRD patients undergoing hemodialysis treatment. Therefore, we designed this study to investigate the acute effects of hemodialysis treatment on spirometry and IOS parameters among CKD patients Materials and Methods: In this cross sectional-descriptive study, the spirometry and IOS were performed twice for the eligible patients: before and immediately after the hemodialysis session. All spirometry tests were done by the same person. The before and after dialysis measured parameters were: forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), vital capacity (VC), the FEV1/FVC ratio, follow rates, and the airway resistance indexes. Results: The spirometry parameters (FEV1, FVC, VC, and the FEV1/FVC) before and after the dialysis had no significant changes (P<0.05 for each parameter). Also, the airway resistance in 5 Hz after the dialysis were changed significantly (P<0.05), while the 20 Hz resistance before and after the dialysis had no significant changes (P> 0.05). Conclusion: In summary, the dialysis can be helpful in improving the patient’s pulmonary functional tests and also the dialysis can improve the patient’s airway resistance. But according to our results, the effect of dialysis on airway resistance especially in the 5Hz was statistically significant. And further studies with bigger study population are recommended for further investigations.

کلیدواژه ها:

Airway resistance ، Hemodialysis ، IOS ، Renal failure.