Systematic review and Meta-analysis of Prevalence blaVIM and blaIMP genes in P. aeruginosa in Iranian patients

سال انتشار: 1397
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 559

نسخه کامل این مقاله ارائه نشده است و در دسترس نمی باشد

استخراج به نرم افزارهای پژوهشی:

لینک ثابت به این مقاله:

شناسه ملی سند علمی:

AMSMED19_226

تاریخ نمایه سازی: 1 دی 1397

چکیده مقاله:

Background and Adjective: Pseudomonas aeruginosa is associated with infection and morality in healthcare envirment. P. aeruginosa carrier blaVIM and blaIMP genes able to destroy beta-lactam antibiotic. The aim of this study is systematic review and meta-analysis of prevalence blaVIM and blaIMP genes in P. aeruginosa in Iranian patient.Search Method: All available national and international databanks (PubMed, Science Direct, Google Scholar, and ISI web of knowledge, IranMedex, SID and Iranmedex) were searched to find published studies from 2006 to 2017. Quality of studies was assessed by STROBE. Because of the significant heterogeneity observed, random effects model was used to combine the results. Statistical analysis was performed by SATA software (CI; 95%, p<0.05). Findings: Final analyze was done on 53 articles relevant with 7797 sample size. Present study indicates that most of the bacteria isolated from wound. Pooled prevalence of blaVIM gene was estimated 9.62%, and blaIMP gene was observed to be 8.43%. Conclusion: Prevalence of blaVIM and blaIMP genes is more in Iranian patients. Therefore it is essential selective antibiotic proscription due to prevention of the prevalence antibiotic resistance. So studies such as case-control retrospective and prospective cohort should have done to calculate prevalence and associate of blaVIM and blaIMP genes with infection in Iranian patient.

کلیدواژه ها:

نویسندگان

Bashir Mohammadpour

Student Research Committee, Kurdistan University of Medical Sciences, Sanandaj, Iran.

Samaneh Rouhi

Cellular and Molecular Research Center, Research Institute for Health Development, Kurdistan University of Medical Sciences, Sanandaj, Iran.

Himen Salimizand

Faculty of Medicine, Kurdistan University of Medical Sciences, Sanandaj, Iran