Changes of serum level of prolactin following the X-ray radiation

Today, many diseases are treatable with x-rays. On the other hand, the rays have harmful effects on human health. Regarding the destructive effects of X-rays on the activity of endocrine glands and possible dysfunction of the hormone caused by their functional impairment, the aim of this study was to investigate changes in serum levels of prolactin following X-rays. 40 male rats were at a weighing range of 250 to 300 g selected randomly. The first group (n=20) was considered as the control group and the second group (n= 20) was exposed to the X-ray once. After the anesthesia of the mice, 2cc of blood were taken from the heart of all of them for hormonal studies. The ELISA method was used to measure serum levels of prolactin. T-Test analysis was used to compare the mean of prolactin level in experimental groups. Data analysis did not show the significant difference in prolactin levels in the X-ray group (19.21±0.76) with compared to the control group (18.98±0.68), (P> 0.05). Therefore, it can be concluded that radiation therapy with X-rays does not have any significant effect on some of the glands and their related hormonal changes.

کلیدواژه ها:

Prolactin ، X-ray radiation ، Serum changes