Alteration of DSC profiles for Halal and non-Halal myoglobins

Biomimetics, simply, is the attempt to mimic physiological properties and functions. Using biology asaguide, we can now understand, engineer, and control bioactive molecular interactions and assemble theminto novel systems or materials.Catalytic nano-architectonics is the art of assembling the desiredfunctionalcomponents according to the scale of catalytic events [1].Herein, a cysteine-metal complex wasdesigned and encapsulated in avesicular mixture (1:4; SDS/DTAB) in order to imitate a chloroperoxidase(CLP) nanozyme via chlorinationof thionine at pH 3. In these experiments, different metals nitrates, zinc,iron, nickel and cobalt were used. First, as biomimetally predicted, Iron chloroperoxidase reactionis donemore quickly than the cobalt,nickel and zinc, respectively.Second, the presentation of mixed SDS/DTABcolloid evolutes the reaction performance because of charges available on surface of hydrophobic nanoenvelopthat provides a particular interface structure for positioning the charged or hydrophobic parts ofactive-site and substrate to locate next to each other at proper direction.

کلیدواژه ها:

cysteine/metal ، SDS/ DTAB ، vesicle ، biomimetic ، chloroperoxidase ، nanozyme