Comparison of Vitamin E and Vitamin D Effects on Primary Dysmenorrhea A Double-Blind Clinical Trial

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 388

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شناسه ملی سند علمی:

COBGY15_231

تاریخ نمایه سازی: 11 آبان 1398

چکیده مقاله:

Introduction: Dysmenorrhea has a prevalence of 50-80% and is one of the most important problems in women, especially in their reproductive age. Various studies have investigated the effect of vitamin D and E supplements. The purpose of this study was to compare the effects of these vitamins on dysmenorrhea.Materials and Methods: This double-blind clinical trial study was conducted in 2016 on 18- to 25-year-old students with moderate to severe dysmenorrhea. Participants were randomly assigned into two groups of vitamin D and E, and the two groups received pain-lowering doses of pain medication for 5 days. The effect of drugs on the severity of dysmenorrhea in two consecutive cycles after supplements was evaluated by VAS and questionnaire. Data were analyzed by SPSS software.Results: 110 female students were enrolled in the study, 10 of whom were excluded from the study. Comparison of mean age and mean BMI between the two groups was not statistically significant. The mean severity of dysmenorrhea based on the VAS instrument before entering the study in vitamin D group was 7.01 ±0.11 and in vitamin E 7.20 ±0.64 .After the first month of consumption in vitamin D group was 5.44±1.40 and vitamin E 5.84±0.84 and After the second month of consumption in the vitamin D group was 5.20 ± 1.34 and vitamin E 5.32 ± 0.68. The results showed that the severity of dysmenorrhea was significantly decreased after supplementations (P <0.001), but there was no statistical difference in the severity of dysmenorrhea between the two groups.Discussion & Conclusion: Vitamin D and Vitamin E are both equally effective in reducing the severity of dysmenorrhea, so these supplements can be used instead of pain relievers.

نویسندگان

Hamideh Pakniat

Assistant Professor, Department of Obstetrics & Gynecology, Qazvin University of Medical Sciences ,Qazvin, Iran