Isolation and structural elucidation of triterpenoid from salvia leriifoliia

The genus Salvia belongs to the Lamiaceae family and comprises numerous species that have been used since ancient times for the treatment of several disorders [1]. Diterpenoids, triterpenoids and polyphenols are very common in plants of this genus. Most Salvia species have been extensively investigated for their potential biological properties [2]. S. leriifolia Benth., that was introduced in the Iranian Flora in 1982, geographically grows in the southern and tropical regions of the Khorassan and Semnan provinces, Iran. Different pharmacological activities of this plant, such as the attenuation of morphine dependence, hypoglycemic, analgesic, and anti-inflammatory activities, and anticonvulsant, antiulcer, and antibacterial effects, were evaluated [3]. Fractionation of hexane extract of S.leriifolia led to the isolation of a triterpenoid(1). Its structure has been established by (1HNMR, 13CNMR and COSY), as well as HRESIMS.