Which method is best for the treatment of hirsutism in women with polycystic ovary syndrome Herbal or Medical

Background and Aim : polycystic ovary syndrome (PCOS), one of the most common causes of infertilitydue to anovulation, affects 4–7% of reproductive women. The aim of this study was to compare the effectof Vitex agnus-castus + fennel + Portulaca with spiernolactone + Cyproterone Compound on hirsutism inpatients with polycystic ovary syndrome in Jahrom city.Methods : This comparative clinical trial was done on 64 PCOS women referred to Dr.rasekh clinic withaged 18-42 years. patients were randomly allocated to either case(32 patients) and control group(32patients). The control group(Medical) prescribed Spirenolactone + Cyproterone Compound and case group(Herbal) Portulaca + Fennel + Vitex agnus-castus daily.Results : There is not significant differences between medical and herbal group in FSH,TSH,DHEA-Slevels after intervention (P> 0.05). LH level decreased significantly after intervention in the herbal group(P = 0.001). There was significant difference in LH level (P = 0.279) in medical group, before and afterintervention. This study showed that there was no significant difference between two groups in terms ofhirsutism (P> 0.05).Menstrual pain (P=0.001 ( and acne were reduction in medical group than herbal group(P=0.026.). Unexpectedly, the results show a decrease in hair loss of herbal group) pvalue=0.001(.Improvement in regular menstrual cycles of herbal group was higher than the medical group,although it was not statistically significant (P=0.316).Conclusion : because of significant effects of herbal regimen on improvement of hirsutism than chemicaldrugs , therefore, we recommend this low costs, low side effect regimen in treatment of hirsutism in PCOSpatients.

کلیدواژه ها:

PCOS ، hirsutism ، Vitex agnus-castus ، fennel ، Portulaca