Electrocatalytic Glucose Oxidation Based on Nickel Nanoparticles/PEDOT: PSS Nanocomposite

Glucose is a simple monosaccharide found in plants. It is one of the three dietary monosaccharides, along with fructose and galactose that are absorbed directly into thebloodstream during digestion. The determination of glucose concentration is very important in clinical, biological samples and chemicals as well as in food processing and fermentation. Many efforts have been tried for the direct electro-oxidation of glucose on different substrates, forexample metal-complex[1-2]. A sensitive non-enzymatic electrochemical glucose sensor with excellent sensitivity, very low detection limit and low glucose oxidation potential was preparedby electrodeposed of nickel nanoparticles on the surface of PEDOT:PSS suspending media.Electrochemical activity of the electrode toward the oxidation of glucose was studied using cyclic voltammetry, chronoamperometry, linear sweep voltammetry and amperometry.Electrochemical measurements indicated that the high sensitivity of 162.91 μAμM-1cm-2 and adetection limit of 0.028 μM was obtain. In addition, the interference from the oxidation of uric acid, dopamine, acetamidophenol and ascorbic acid could be effectively avoided. Meanwhile, the non-enzymatic glucose sensors exhibited excellent selectivity, stability and repeatability. Thus, this novel non-enzyme sensor has potential application in glucose detection [3-4].

کلیدواژه ها:

Glucose ، Nanoparticle ، Sensor ، PEDOT: PSS