Application of nanocarriers for drug delivery

Introduction: In recent years, attention to the use of nanoparticles as carriers for drug delivery to different parts of the body. By changing the pharmacokinetic characteristics of drug, nanocarriers lead to better performance and decrease the side effects of drug. In this study first of nanocarriers, how to produce it and then nanocarrier new applications in drug delivery systems are discussed.Results: hydrogel SB50 to Batrvksvbyn reputation. In fact it is produced from engineered bacteria. The hydrogel containing nanofibers obtained by combining the serpent poison and is used to prevent bleeding. Another example is the use of nanocarriers to treat tularemia. Tularemia or rabbit fever, is a disease caused by bacteria Francisella tularensis. Disease through skin contact, contaminated drinking water, breathing contaminated dust, scratching the infected animals transmitted to humans. In a study on animals nanoparticle containing the antibiotic moxifloxacin production. After the injection of nanocarriers, silica nanoparticles in macrophages easily devour the ideal particles produce infection. Another example is the nanocarriers 3HM . The nanocarrier of hydrophobic and hydrophilic polymers consists of two parts that are able to cross the blood-brain barrier is formed in large amounts in Glioblastoma tumors accumulate and eventually kill them.Conclusion: Given that more effective drug nanocarriers were able to protect the drug molecule is therefore better to treat the disease, helped with the production of nanocarriers.

کلیدواژه ها:

nanocarrier ، hydrogel SB50 ، bacteria Francisella tularensis ، Glioblastoma tumors