Chitosan nanofibers and their applications in skin tissue engineering

سال انتشار: 1391
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 1,362

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شناسه ملی سند علمی:

IAUET01_106

تاریخ نمایه سازی: 9 تیر 1392

چکیده مقاله:

Chitosan possess effective antimicrobial, hemostatic and wound-healing acceleration properties, which has found wide applications in wound and burn treatment. Chitosan nanofibrous scaffolds produced via electrospinning are architecturally similar to the fibrillar structure of the extracellular matrix that leads to enhancement of cell adhesion and proliferation and also improvement of tissue regeneration. In this article, we reviewed the reports on preparation of electrospun nanofibrous scaffolds of chitosan and composite scaffolds of chitosan and biocompatible polymers. Furthermore, the characteristics of these biomaterials, biological properties of chitosan in combination with biocompatible polymers, behaviors of skin cells on the scaffolds and their effects on the skin regeneration as wound dressings are discussed.

نویسندگان

Mohammad Norouzi

Young Researchers and Elites Club, Science and Research Branch, Islamic Azad University, Tehran, Iran -Department of Nanotechnology and Tissue Engineering, Stem Cell Technology Research Center, Tehran, Iran

Masoud Soleimani

Department of Hematology, Faculty of Medical Sciences, Tarbiat Modares University, Tehran, Iran

Hamideh Moravvej

Department of Dermatology, Skin Research Center, Shaheed Beheshti University of Medical Sciences, Tehran, Iran

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