Air pollution and admissions due to ST elevation myocardial infarction—a time-series study from northwest of Iran

Introduction: We investigated the association between the levels of air pollutants and the number of daily admissions due to ST segment elevation myocardial infarction (STEMI) in a metropolitan in the northwest of Iran.Methods: Daily concentrations of common air pollutants were obtained for the greater city of Tabriz for a period of 2 years. These reports included sulfur dioxide (SO2), nitrogen dioxide (NO2), nitric oxide (NO), nitrogen byproducts (NOx), carbon monoxide (CO), ozone (O3), and particulate matters < 10 μm (PM10). The census of admissions for STEMI was retrieved for the same period from hospital registries. The association of daily variations in air pollutant levels and the daily number of STEMI admissions were investigated in a time-series analysis.Results: In the multi-pollutant model adjusting for long-term trend, seasonality, and temperature, a significant association was found for 1-h [NO2] and 24-h [CO]. A marginally significant association was observed for 24-h [NO2] and 8-h [CO]. The 24-h [CO] had the strongest association with thenumber of admissions with STEMI. Maximum 1-h concentrations of NO2 onthe same day and on the prior day as well as 24-h concentrations of CO on theprior day were independently associated with increased number of STEMIadmissions.Conclusion: However, daily concentrations of SO2, NO, O3, and PM10 werenot associated with the frequency of hospital admissions for STEMI

کلیدواژه ها:

Air pollution ، Myocardial infarction ، Nitrogen dioxide ، Carbonmonoxide ، Nitric oxide ، Ozone