Phenotype mupirocin resistance and antibiotic resistance patterns of Staphylococcus aureus isolated from the Pasteur hospital staffnose of Bam 2016

Introduction and Objectives: Mupirocin is a topical antibiotic. This antibiotic inhibits the activity of most gram-positive cocci. Mupirocin inhibits bacterial protein production competitively. This antibiotic is used to treat staphylococcal skin infections and the removal of Staphylococcus aureus nasal carriers. The aim of this study Phenotype mupirocin resistance and antibiotic resistance patterns of S. aureus isolated from the Pasteur hospital staffnose of Bam.Materials and Methods: Nasal samples were collected from 120hospital staffnose. S.aureus was identified using standard methods. The antibiotic susceptibility test was performed according to Clinical and Laboratory Standards Institute (CLSI) and the data was processed using SPSS software.Result: From 150 samples, 40 species of Staphylococcus aureus (26.66%) were obtained. Five species (12.5%) were resistant to mupirocin. The highest resistance to clindamycin and co-trimoxazole (45%) and the least resistance to tetracycline (0%) was observed.Conclusion: Due to the fact that S. aureus is a hospital infection and hospital personnel can act as carriers, the use of mupirocin ointment as an effective factor in the removal of this bacterium from nasal carriers is still effective and there was not a high number of resistance.

کلیدواژه ها:

mupirocin ، Staphylococcus aureus ، nasal carriers ، antibiotic resistance