Frequency of Microorganisms Isolated From Blood Cultures of Hospitalized Patients in Shiraz, March 2017 to March 2018

Introduction and Objectives: Bloodstream infections (BSIs) are associated with significant patient morbidity and mortality in hospitalized patients. Blood culture plays an important role in identifying most of bacterial agents of bloodstream infections. Therefore, the aim of the present study was to determine the prevalence of various bacterial isolates causing sepsis in Shiraz hospitals.Materials and methods: This retrospective study was conductedduring a one-year period (March 2017 to March 2018). After identifying the types of bacterial by standard identification test, API bacterial identification and BD PHOENIX Automated system, susceptibility testing was performed according toCLSI standards, and the results were analyzed with WHONET software.Results: Approximately 7980 blood culture bottles received in the Professor Alborzi Clinical Microbiology Research Center. Of these cultures, 1373 (17.20%) were positive; 604 (%) and 769 (54%) were from females and males, respectively. Most of the positive cultures were related to the emergency wards with 612 cases (45%), Pediatric medical ward with 170 cases (12%) and NICU with 138 cases (10%). Stenotrophomonase maltophilia (33.66%), Pseudomonas spp (8.23%), Enterococcus spp (7.93%), Acinetobacter calcoaceticus baumannii (Acb) complex (6.04%) and Escherichia coli (5.97) were the most frequently isolated bacteria from blood cultures.Conclusion: S. maltophilia was most commonly isolated from bloodstream infections. The treatment of infections by S.maltophilia is difficult, as this pathogen shows high levels of intrinsic or acquired resistance to different antimicrobial agents, drastically reducing the antibiotic options available for treatment. As its isolation is increasing, it is important to study the epidemiology and antimicrobial susceptibility profile of these isolates.

کلیدواژه ها:

Microorganisms ، Blood Cultures ، Shiraz