Evaluation Frequency of Germ type, Clinical symptoms and Antimicrobial Resistance Pattern in Children with UTI in Khorramabad

سال انتشار: 1398
نوع سند: مقاله کنفرانسی
زبان: انگلیسی
مشاهده: 328

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شناسه ملی سند علمی:

ICCM13_183

تاریخ نمایه سازی: 25 آبان 1398

چکیده مقاله:

Background and Objectives: Urinary tract infection is one of the most commonly known infections in children. Investigating the causative agents associated with this infection can be useful in the prevention and treatment of this infection. The purpose of this study was to investigate the frequency distribution of germ type, clinical signs and antibiotic resistance in children with urinary tract infection in the city of Khoramabad. Materials and Methods: This cross-sectional study was conducted on descriptive and analytic epidemiology by census method based on hospital and clinic data on patients under 16 years of age who had a urinary tract infection referred to the Madani Clinic of Kurumbabad . Information about these patients, including age, sex, type of urinary tract infection in terms of anatomical position of the infection, the type of microorganism determined based on the samples taken from the patient, antibiotic resistance and microorganism susceptibility to the existing antimicrobial agents using antibiogram test were collected and analyzed according to the goals defined in the study. Results: In this study, 150 patients were studied of which 59.3% were women and 40.7% were men. The highest frequency of urinary tract infections was in the age group of 1-5 years (48.7%), followed by the age group of 1 month to 1 year (28%), over 5 years (18%) and under 1 month (5.5%). 72.7% of infections were related to the upper urinary tract infection and 27.3% were related to the subcutaneous urinary tract infection. The most common urinary tract infection associated microorganisms were E. coli (72 %), followed by Proteus (14%), Klebsiella (7.7%), Enterococci (4.7%) and citrobacter (1.3%). In 78.7% of patients fever, 64% burning and frequent urination and, 16% with reduced appetite and 13.3% stomach ache were, however, in the other patients no symptoms were identified. Escherichia coli and Proteus showed the highest resistance to Ampicillin, Klebsiella and Enterobacter showed the highest resistance to Ampicillin and Amoxicillin and Citrobacter showed the highest resistance to Amoxicillin. The highest susceptibility was observed for Escherichia coli against Amicacin, for proteus against ceftriaxone and Amicacin, for Klebsiella against ciprofloxacin, for enterobacter against ceftriaxone, cefixime, ciprofloxacin, amicacin and citrobacter showed complete susceptibility against all studied antibiotics. No significant relationship was found between age and sex with the type of bacteria causing UTI infection. Conclusion: Antibiotic resistance was observed in a different pattern in patients with UTI. Further cross-sectional and regional studies are needed to evaluate the bacterial resistance to antibiotics.

نویسندگان

Hamid Reza Sherkatolabbasieh

Department of pediatric Medicine,Lorestan University of Medical Sciences,Khorramabad,Iran

Maryam Nikroo

Department of pediatric Medicine,Lorestan University of Medical Sciences,Khorramabad,Iran

Aliakbar Razlansary

Department of pediatric Medicine,Lorestan University of Medical Sciences,Khorramabad,Iran

Shiva Shafizadeh

Department of pediatric Medicine,Lorestan University of Medical Sciences,Khorramabad,Iran