Selective and facile Synthesis of 2-Aminothiophenes Using Na2CaP2O7 as base Nano-Catalyst

In the study we reported synthesis of 2-aminothiophene derivatives in pure water using nano-structured Na2CaP2O7. Our results indicated that this heterogeneous catalyst performed good selectivity and catalytic activity in the synthesis of substituted 2- aminothiophene through Gewald reaction in water. The noticeable benefits of this procedure rely on several factors including: a simple method, mildness conditions, short time of reaction, operational simplicity and low cost.

کلیدواژه ها:

2-Aminothiophenes ، Gewald reaction ، nanocatalyst ، Na2CaP2O7