HN-02250220_Effects Capsinoid and Fermented Red Pepper Paste Supplementation on Body Composition and Anthropometric Measures: A Systematic Review and Meta-Analysis of Randomized Controlled Trials

Introduction: Current systematic review and meta-analysis was done on the effects of Capsinoid and fermented red pepper paste supplementation on body composition and anthropometric measures.Methods: We searched PubMed, SCOPUS, Cochrane Library and Google Scholar from inception to October 2019 using relevant keywords. Weighted mean differences (WMDs) were analyzed using a random-effects model.Results: Overall, 14 trials were included. Pooled effect sizes suggested a significant effect of Capsinoid and fermented red pepper paste administration on body weight (BW)(WMD: -0.38 kg; 95% CI: -0.70, -0.06, P=0.02) and visceral fat area (VFA)(WMD: -3.27 cm2, 95% CI: -4.74, -1.80, P<0.001) whereas changes in body mass index (BMI)(WMD: -0.04 kg/m2, 95% CI: -0.13, 0.05, P=0.362), waist circumference (WC)(WMD: -0.20 cm, 95% CI: -1.16, 0.76, P=0.683), waist-hip ratio (WHR)(WMD: -0.05, 95% CI: -0.65, 0.55, P=0.877), fat mass (FM)(WMD: -0.17 kg, 95% CI: -0.61, 0.27, P=0.450), fat free mass (FFM)(WMD: -0.05 kg, 95% CI: -0.65, 0.55, P=0.877), total fat area (TFA)(WMD: -5.84 cm2, 95% CI: -16.52, 4.83, P=0.283), subcutaneous fat area (SFA)(WMD: -2.07 cm2, 95% CI: -11.39, 7.26, P=0.664) and percentage body fat (PBF)(WMD: 0.01 %, 95% CI: -0.59, 0.61, P=0.985) was not statistically significant. Findings from subgroup analysis revealed a significant reduction in TFA and SFA in trials using supplementation of Capsinoid, with dosage of 135≤ and age of 23<.Conclusion: Taken together, the data suggest that Capsinoid and fermented red pepper paste supplementation has beneficial effects to reduce BW and VFA, but not BMI, WC, WHR, FM, FFM, TFA, SFA and PBF.

کلیدواژه ها:

meta-analysis ، obesity ، Capsinoid ، red pepper ، weight