Sensitive voltammetric determination of antipsychotic perphenazine using multiwall carbon nanotube-ionic liquid nanocomposite electrode

Using the unique properties of carbon-ionic liquid nanocomposites, a sensitive electrochemical sensor fordetermination of perphenazine, a common antipsychotic drug, has been fabricated. Differential pulse voltammetry wasapplied as an analytical technique for quantification of sub-micromolar concentrations of perphenazine. The surfacemorphology of composite electrode was characterized by scanning electron microscopy. Various parameters wereoptimized for practical applications. Under the selected conditions, theproposed electrode exhibited interesting sensitivitytoward determination of perphenazine compared to the other conventional electrodes and the anodic peak current versusPPZ concentration was linear in the range of 0.05-30 μM.

کلیدواژه ها:

Carbon nanotube-ionic liquid nanocomposite ، Differential pulse voltammetry ، Perphenazine